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The Vertebrate Claudin/PMP22/EMP22/MP20 family protein TMEM47 Regulates Epithelial Cell Junction Maturation and Morphogenesis

BACKGROUND: TMEM47 is the vertebrate orthologue of C. elegans VAB-9, a tetraspan adherens junction protein in the PMP22/EMP/Claudin family of proteins. VAB-9 regulates cell morphology and adhesion in C. elegans and TMEM47 is expressed during kidney development and regulates the activity of Fyn. The...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Dev Dyn
Hauptverfasser: Dong, Yi, Simske, Jeffrey S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322768/
https://ncbi.nlm.nih.gov/pubmed/26990309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24404
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