The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

Senescence is a form of cell cycle arrest induced by stress such as DNA damage and oncogenes. However, while arrested, senescent cells secrete a variety of proteins collectively known as the senescence-associated secretory phenotype (SASP), which can reinforce the arrest and induce senescence in a p...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Ritschka, Birgit, Storer, Mekayla, Mas, Alba, Heinzmann, Florian, Ortells, Mari Carmen, Morton, Jennifer P., Sansom, Owen J., Zender, Lars, Keyes, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322731/
https://ncbi.nlm.nih.gov/pubmed/28143833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.290635.116
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