Outer Plexiform Layer Structures Are Not Altered Following AAV-Mediated Gene Transfer in Healthy Rat Retina

Ocular gene therapy approaches have been developed for a variety of different diseases. In particular, clinical gene therapy trials for RPE65 mutations, X-linked retinoschisis, and choroideremia have been conducted at different centers in recent years, showing that adeno-associated virus (AAV)-media...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Giers, Bert C., Klein, Daniela, Mendes-Madeira, Alexandra, Isiegas, Carolina, Lorenz, Birgit, Haverkamp, Silke, Stieger, Knut
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322291/
https://ncbi.nlm.nih.gov/pubmed/28280483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00059
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