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MKR mice have increased dynamic glucose disposal despite metabolic inflexibility, and hepatic and peripheral insulin insensitivity

AIMS/HYPOTHESIS: Recent work has shown that there can be significant differences when glucose disposal is assessed for high-fat induced insulin resistance by static clamp methods vs dynamic assessment during a stable isotope i.p. glucose tolerance test. MKR mice, though lean, have severe insulin res...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Vaitheesvaran, B., LeRoith, D., Kurland, I. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322278/
https://ncbi.nlm.nih.gov/pubmed/20577711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1827-4
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