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In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects.

To determine whether abnormal kinetics of insulin's biologic actions contribute to the overall insulin resistance in obesity, we compared the rate of activation and deactivation of insulin's effects to stimulate glucose disposal rate (Rd) and inhibit hepatic glucose output (HGO) in 12 nono...

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Autores principales: Prager, R, Wallace, P, Olefsky, J M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC423584/
https://ncbi.nlm.nih.gov/pubmed/3525609
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