System-based proteomic and metabonomic analysis of the Df(16)A(+/−) mouse identifies potential miR-185 targets and molecular pathway alterations

Deletions on chromosome 22q11.2 are a strong genetic risk factor for development of schizophrenia and cognitive dysfunction. We employed shotgun liquid chromatography–mass spectrometry (LC-MS) proteomic and metabonomic profiling approaches on prefrontal cortex (PFC) and hippocampal (HPC) tissue from...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Wesseling, H, Xu, B, Want, E J, Holmes, E, Guest, P C, Karayiorgou, M, Gogos, J A, Bahn, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322275/
https://ncbi.nlm.nih.gov/pubmed/27001617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.27
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