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IL-10Rα expression is post-transcriptionally regulated by miR-15a, miR-185, and miR-211 in melanoma

BACKGROUND: IL-10 is an immunoregulatory cytokine that increases during malignant diseases. The purpose of this study was to: i) determine the mRNA amounts of IL-10, IL-10Rα, and IL-10Rβ in cutaneous and uveal melanoma cells and specimens; ii) evaluate their post-transcriptional regulation by miRNAs...

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Bibliografiska uppgifter
I publikationen:BMC Med Genomics
Huvudupphovsmän: Venza, Isabella, Visalli, Maria, Beninati, Concetta, Benfatto, Salvatore, Teti, Diana, Venza, Mario
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668633/
https://ncbi.nlm.nih.gov/pubmed/26631117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0156-3
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