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Block ionomer complexes consisting of siRNA and aRAFT-synthesized hydrophilic-block-cationic copolymers II: The influence of cationic block charge density on gene suppression

Block ionomer complex (BIC)-siRNA interactions and effectiveness in cell transfection are reported. Aqueous RAFT polymerization was used to prepare a series of hydrophilic-block-cationic copolymers in which the cationic block statistically incorporates increasing amounts of neutral, hydrophilic mono...

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Pubblicato in:Polym Chem
Autori principali: Parsons, Keith H., Holley, Andrew C., Munn, Gabrielle A., Flynt, Alex S., McCormick, Charles L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321653/
https://ncbi.nlm.nih.gov/pubmed/28239425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6PY01048B
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