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A sestrin-dependent Erk/Jnk/p38 MAPK activation complex inhibits immunity during ageing
Mitogen activated protein kinases (MAPKs) including Erk, Jnk and p38 regulate diverse cellular functions, and are thought to be controlled by independent upstream activation cascades. Here we show that the sestrins bind to and co-ordinate simultaneous Erk, Jnk and p38 MAPK activation in T lymphocyte...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321575/ https://ncbi.nlm.nih.gov/pubmed/28114291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3665 |
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