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Probing of Amyloid Aβ (14–23) Trimers by Single-Molecule Force Spectroscopy

Self-assembly and aggregation of amyloid peptides, such as Aβ(1–40) and Aβ(1–42), lead to the development of Alzheimer disease and similar neurodegenerative disorders associated with protein aggregation. The structures of large aggregates, specifically fibrils, are well characterized. However, our u...

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Détails bibliographiques
Publié dans:Jacobs J Mol Transl Med
Auteurs principaux: Maity, Sibaprasad, Lyubchenko, Yuri L.
Format: Artigo
Langue:Inglês
Publié: 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321571/
https://ncbi.nlm.nih.gov/pubmed/28239686
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