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Probing of Amyloid Aβ (14–23) Trimers by Single-Molecule Force Spectroscopy

Self-assembly and aggregation of amyloid peptides, such as Aβ(1–40) and Aβ(1–42), lead to the development of Alzheimer disease and similar neurodegenerative disorders associated with protein aggregation. The structures of large aggregates, specifically fibrils, are well characterized. However, our u...

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Bibliografische gegevens
Gepubliceerd in:Jacobs J Mol Transl Med
Hoofdauteurs: Maity, Sibaprasad, Lyubchenko, Yuri L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321571/
https://ncbi.nlm.nih.gov/pubmed/28239686
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