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Probing of Amyloid Aβ (14–23) Trimers by Single-Molecule Force Spectroscopy

Self-assembly and aggregation of amyloid peptides, such as Aβ(1–40) and Aβ(1–42), lead to the development of Alzheimer disease and similar neurodegenerative disorders associated with protein aggregation. The structures of large aggregates, specifically fibrils, are well characterized. However, our u...

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Detalhes bibliográficos
Publicado no:Jacobs J Mol Transl Med
Main Authors: Maity, Sibaprasad, Lyubchenko, Yuri L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321571/
https://ncbi.nlm.nih.gov/pubmed/28239686
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