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Direct visualization of glutamate transporter elevator mechanism by high-speed AFM

Glutamate transporters are essential for recovery of the neurotransmitter glutamate from the synaptic cleft. Crystal structures in the outward- and inward-facing conformations of a glutamate transporter homolog from archaebacterium Pyrococcus horikoshii, sodium/aspartate symporter Glt(Ph), suggested...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ruan, Yi, Miyagi, Atsushi, Wang, Xiaoyu, Chami, Mohamed, Boudker, Olga, Scheuring, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320997/
https://ncbi.nlm.nih.gov/pubmed/28137870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616413114
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