Endothelial Wnt/β-catenin signaling reduces immune cell infiltration in multiple sclerosis

Disruption of the blood–brain barrier (BBB) is a defining and early feature of multiple sclerosis (MS) that directly damages the central nervous system (CNS), promotes immune cell infiltration, and influences clinical outcomes. There is an urgent need for new therapies to protect and restore BBB fun...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lengfeld, Justin E., Lutz, Sarah E., Smith, Julian R., Diaconu, Claudiu, Scott, Cameron, Kofman, Sigal B., Choi, Claire, Walsh, Craig M., Raine, Cedric S., Agalliu, Ilir, Agalliu, Dritan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320985/
https://ncbi.nlm.nih.gov/pubmed/28137846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609905114
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