Endothelial Wnt/β-catenin signaling reduces immune cell infiltration in multiple sclerosis

Disruption of the blood–brain barrier (BBB) is a defining and early feature of multiple sclerosis (MS) that directly damages the central nervous system (CNS), promotes immune cell infiltration, and influences clinical outcomes. There is an urgent need for new therapies to protect and restore BBB fun...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Lengfeld, Justin E., Lutz, Sarah E., Smith, Julian R., Diaconu, Claudiu, Scott, Cameron, Kofman, Sigal B., Choi, Claire, Walsh, Craig M., Raine, Cedric S., Agalliu, Ilir, Agalliu, Dritan
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2017
主題:
PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320985/
https://ncbi.nlm.nih.gov/pubmed/28137846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609905114
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