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Mechanisms of Action of Lenalidomide in B-Cell Non-Hodgkin Lymphoma

Lenalidomide is an orally active immunomodulatory drug that has direct antineoplastic activity and indirect effects mediated through multiple types of immune cells found in the tumor microenvironment, including B, T, natural killer (NK), and dendritic cells. Recently, the E3 ubiquitin ligase cereblo...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Gribben, John G., Fowler, Nathan, Morschhauser, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320950/
https://ncbi.nlm.nih.gov/pubmed/26195701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.59.5363
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