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Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma

Obinutuzumab (GA101) is a type II, glycoengineered anti-CD20 monoclonal antibody for the treatment of hematologic malignancies. Obinutuzumab has mechanisms of action that are distinct from those of rituximab, potentially translating into improved clinical efficacy. We present the pharmacokinetic and...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Cartron, Guillaume, Hourcade-Potelleret, Florence, Morschhauser, Franck, Salles, Gilles, Wenger, Michael, Truppel-Hartmann, Anna, Carlile, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938339/
https://ncbi.nlm.nih.gov/pubmed/26659915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.133421
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