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Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma

Obinutuzumab (GA101) is a type II, glycoengineered anti-CD20 monoclonal antibody for the treatment of hematologic malignancies. Obinutuzumab has mechanisms of action that are distinct from those of rituximab, potentially translating into improved clinical efficacy. We present the pharmacokinetic and...

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Dettagli Bibliografici
Pubblicato in:Haematologica
Autori principali: Cartron, Guillaume, Hourcade-Potelleret, Florence, Morschhauser, Franck, Salles, Gilles, Wenger, Michael, Truppel-Hartmann, Anna, Carlile, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938339/
https://ncbi.nlm.nih.gov/pubmed/26659915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.133421
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