Dendritic cells, macrophages, NK and CD8(+) T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B

BACKGROUND: Herpes simplex virus type 1 (HSV-1) cause not only mild symptoms but also blindness and encephalitis. It was previously shown that the immune response against HSV-1 occurs mainly in the trigeminal ganglia (TG) and that Toll-like receptors 2 and 9 (TLR2/9) are important in mediating this...

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Detalles Bibliográficos
Publicado en:Virol J
Main Authors: Lucinda, Natália, Figueiredo, Maria Marta, Pessoa, Natália Lima, Santos, Beatriz Senra Álvares da Silva, Lima, Graciela Kunrath, Freitas, Arthur Molinari, Machado, Alexandre Magalhães Vieira, Kroon, Erna Geessien, Antonelli, Lis Ribeiro do Valle, Campos, Marco Antônio
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320739/
https://ncbi.nlm.nih.gov/pubmed/28222752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0692-x
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