Dendritic cells, macrophages, NK and CD8(+) T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B

BACKGROUND: Herpes simplex virus type 1 (HSV-1) cause not only mild symptoms but also blindness and encephalitis. It was previously shown that the immune response against HSV-1 occurs mainly in the trigeminal ganglia (TG) and that Toll-like receptors 2 and 9 (TLR2/9) are important in mediating this...

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Библиографические подробности
Опубликовано в: :Virol J
Главные авторы: Lucinda, Natália, Figueiredo, Maria Marta, Pessoa, Natália Lima, Santos, Beatriz Senra Álvares da Silva, Lima, Graciela Kunrath, Freitas, Arthur Molinari, Machado, Alexandre Magalhães Vieira, Kroon, Erna Geessien, Antonelli, Lis Ribeiro do Valle, Campos, Marco Antônio
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320739/
https://ncbi.nlm.nih.gov/pubmed/28222752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0692-x
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