Plasma from pre-pubertal obese children impairs insulin stimulated Nitric Oxide (NO) bioavailability in endothelial cells: Role of ER stress

Childhood obesity is commonly associated with early signs of endothelial dysfunction, characterized by impairment of insulin signaling and vascular Nitric Oxide (NO) availability. However, the underlying mechanisms remain to be established. Hence, we tested the hypothesis that endothelial insulin-st...

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Publicat a:Mol Cell Endocrinol
Autors principals: Di Pietro, Natalia, Marcovecchio, M. Loredana, Di Silvestre, Sara, de Giorgis, Tommaso, Cordone, Vincenzo Giuseppe Pio, Lanuti, Paola, Chiarelli, Francesco, Bologna, Giuseppina, Mohn, Angelika, Pandolfi, Assunta
Format: Artigo
Idioma:Inglês
Publicat: North Holland Publishing 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320395/
https://ncbi.nlm.nih.gov/pubmed/28062198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2017.01.001
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