Plasma from pre-pubertal obese children impairs insulin stimulated Nitric Oxide (NO) bioavailability in endothelial cells: Role of ER stress

Childhood obesity is commonly associated with early signs of endothelial dysfunction, characterized by impairment of insulin signaling and vascular Nitric Oxide (NO) availability. However, the underlying mechanisms remain to be established. Hence, we tested the hypothesis that endothelial insulin-st...

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Bibliografiske detaljer
Udgivet i:Mol Cell Endocrinol
Main Authors: Di Pietro, Natalia, Marcovecchio, M. Loredana, Di Silvestre, Sara, de Giorgis, Tommaso, Cordone, Vincenzo Giuseppe Pio, Lanuti, Paola, Chiarelli, Francesco, Bologna, Giuseppina, Mohn, Angelika, Pandolfi, Assunta
Format: Artigo
Sprog:Inglês
Udgivet: North Holland Publishing 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320395/
https://ncbi.nlm.nih.gov/pubmed/28062198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2017.01.001
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