Hypofibrinolytic State in Subjects with Type 2 Diabetes Mellitus Aggravated by the Metabolic Syndrome before Clinical Manifestations of Atherothrombotic Disease

Background. Metabolic and genetic factors induce plasminogen activator inhibitor type-1 (PAI-1) overexpression; higher PAI-1 levels decrease fibrinolysis and promote atherothrombosis. Aim. To assess PAI-1 antigen levels among subjects with type 2 diabetes mellitus (T2DM) plus Metabolic Syndrome (Met...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Aburto-Mejía, Elsa, Santiago-Germán, David, Martínez-Marino, Manuel, María Eugenia Galván-Plata, Almeida-Gutiérrez, Eduardo, López-Alarcón, Mardia, Hernández-Juárez, Jesús, Alvarado-Moreno, Antonio, Leaños-Miranda, Alfredo, Majluf-Cruz, Abraham, Isordia-Salas, Irma
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320378/
https://ncbi.nlm.nih.gov/pubmed/28271069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6519704
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