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Hypofibrinolytic State in Subjects with Type 2 Diabetes Mellitus Aggravated by the Metabolic Syndrome before Clinical Manifestations of Atherothrombotic Disease

Background. Metabolic and genetic factors induce plasminogen activator inhibitor type-1 (PAI-1) overexpression; higher PAI-1 levels decrease fibrinolysis and promote atherothrombosis. Aim. To assess PAI-1 antigen levels among subjects with type 2 diabetes mellitus (T2DM) plus Metabolic Syndrome (Met...

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Detalhes bibliográficos
Main Authors: Elsa Aburto-Mejía, David Santiago-Germán, Manuel Martínez-Marino, María Eugenia Galván-Plata, Eduardo Almeida-Gutiérrez, Mardia López-Alarcón, Jesús Hernández-Juárez, Antonio Alvarado-Moreno, Alfredo Leaños-Miranda, Abraham Majluf-Cruz, Irma Isordia-Salas
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2017-01-01
Colecção:BioMed Research International
Acesso em linha:http://dx.doi.org/10.1155/2017/6519704
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