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The Na(+)/H(+) Exchanger Regulatory Factor Stabilizes Epidermal Growth Factor Receptors at the Cell Surface

Ligand binding to cell surface receptors initiates both signal transduction and endocytosis. Although signaling may continue within the endocytic compartment, down-regulation is the major mechanism that controls the concentration of cell surface receptors, their ability to receive environmental sign...

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Detalles Bibliográficos
Main Authors: Lazar, Cheri S., Cresson, Catherine M., Lauffenburger, Douglas A., Gill, Gordon N.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC532026/
https://ncbi.nlm.nih.gov/pubmed/15469991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0239
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