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The Na(+)/H(+) Exchanger Regulatory Factor Stabilizes Epidermal Growth Factor Receptors at the Cell Surface

Ligand binding to cell surface receptors initiates both signal transduction and endocytosis. Although signaling may continue within the endocytic compartment, down-regulation is the major mechanism that controls the concentration of cell surface receptors, their ability to receive environmental sign...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Lazar, Cheri S., Cresson, Catherine M., Lauffenburger, Douglas A., Gill, Gordon N.
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC532026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15469991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-03-0239
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