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The Na(+)/H(+) Exchanger Regulatory Factor Stabilizes Epidermal Growth Factor Receptors at the Cell Surface

Ligand binding to cell surface receptors initiates both signal transduction and endocytosis. Although signaling may continue within the endocytic compartment, down-regulation is the major mechanism that controls the concentration of cell surface receptors, their ability to receive environmental sign...

詳細記述

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書誌詳細
主要な著者: Lazar, Cheri S., Cresson, Catherine M., Lauffenburger, Douglas A., Gill, Gordon N.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC532026/
https://ncbi.nlm.nih.gov/pubmed/15469991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-03-0239
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