Evaluation of impact of anti-idursulfase antibodies during long-term idursulfase enzyme replacement therapy in mucopolysaccharidosis II patients

OBJECTIVES: This 109-week, nonrandomized, observational study of mucopolysaccharidosis II (MPS II) patients already enrolled in the Hunter Outcome Survey (HOS) (NCT00882921), assessed the long-term immunogenicity of idursulfase, and examined the effect of idursulfase-specific antibody generation on...

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Foilsithe in:Mol Genet Metab Rep
Main Authors: Giugliani, R., Harmatz, P., Jones, S.A., Mendelsohn, N.J., Vellodi, A., Qiu, Y., Hendriksz, C.J., Vijayaraghavan, S., Whiteman, D.A.H., Pano, A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2017
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320046/
https://ncbi.nlm.nih.gov/pubmed/28243577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2017.01.014
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