Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality

BACKGROUND: The purposes of this study are to examine if the human glucocorticoid receptor (hGR) isoform-α mRNA and hGR protein expressions are deficient in the acute phase of sepsis (S) compared to systemic inflammatory response syndrome (SIRS) and healthy subjects (H) and to evaluate if the hGRα a...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Intensive Care Med Exp
Autori principali: Vardas, Konstantinos, Ilia, Stavroula, Sertedaki, Amalia, Charmandari, Evangelia, Briassouli, Efrossini, Goukos, Dimitris, Apostolou, Kleovoulos, Psarra, Katerina, Botoula, Efthimia, Tsagarakis, Stylianos, Magira, Eleni, Routsi, Christina, Stratakis, Constantine A., Nanas, Serafim, Briassoulis, George
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319939/
https://ncbi.nlm.nih.gov/pubmed/28224564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0123-8
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