Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality

BACKGROUND: The purposes of this study are to examine if the human glucocorticoid receptor (hGR) isoform-α mRNA and hGR protein expressions are deficient in the acute phase of sepsis (S) compared to systemic inflammatory response syndrome (SIRS) and healthy subjects (H) and to evaluate if the hGRα a...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Vardas, Konstantinos, Ilia, Stavroula, Sertedaki, Amalia, Charmandari, Evangelia, Briassouli, Efrossini, Goukos, Dimitris, Apostolou, Kleovoulos, Psarra, Katerina, Botoula, Efthimia, Tsagarakis, Stylianos, Magira, Eleni, Routsi, Christina, Stratakis, Constantine A., Nanas, Serafim, Briassoulis, George
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319939/
https://ncbi.nlm.nih.gov/pubmed/28224564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0123-8
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