Rapid turnover of DnaA at replication origin regions contributes to initiation control of DNA replication

DnaA is a conserved key regulator of replication initiation in bacteria, and is homologous to ORC proteins in archaea and in eukaryotic cells. The ATPase binds to several high affinity binding sites at the origin region and upon an unknown molecular trigger, spreads to several adjacent sites, induci...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Schenk, Katrin, Hervás, Ana B., Rösch, Thomas C., Eisemann, Marc, Schmitt, Bernhard A., Dahlke, Stephan, Kleine-Borgmann, Luise, Murray, Seán M., Graumann, Peter L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319796/
https://ncbi.nlm.nih.gov/pubmed/28166228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006561
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