Structural basis of replication origin recognition by the DnaA protein

Escherichia coli DnaA binds to 9 bp sequences (DnaA boxes) in the replication origin, oriC, to form a complex initiating chromosomal DNA replication. In the present study, we determined the crystal structure of its DNA-binding domain (domain IV) complexed with a DnaA box at 2.1 Å resolution. DnaA do...

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Main Authors: Fujikawa, Norie, Kurumizaka, Hitoshi, Nureki, Osamu, Terada, Takaho, Shirouzu, Mikako, Katayama, Tsutomu, Yokoyama, Shigeyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153737/
https://ncbi.nlm.nih.gov/pubmed/12682358
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