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Revealing the Concealed Nature of Long QT Type 3 Syndrome

BACKGROUND: Gain-of-function mutations in the voltage-gated sodium channel (Nav1.5) are associated with the long QT-3 (LQT3) syndrome. Nav1.5 is densely expressed at the intercalated disk, and narrow intercellular separation can modulate cell-to-cell coupling via extracellular electric fields and de...

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Publicat a:Circ Arrhythm Electrophysiol
Autors principals: Greer-Short, Amara, George, Sharon A., Poelzing, Steven, Weinberg, Seth H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319726/
https://ncbi.nlm.nih.gov/pubmed/28213505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.116.004400
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