Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia

Whether neuronal inositol-requiring enzyme 1 (Ire1) is required for the proper regulation of energy balance and glucose homeostasis is unclear. We found that pro-opiomelanocortin (Pomc)–specific deficiency of Ire1α accelerated diet-induced obesity concomitant with a decrease in energy expenditure. T...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Yao, Ting, Deng, Zhuo, Gao, Yong, Sun, Jia, Kong, Xingxing, Huang, Yiru, He, Zhenyan, Xu, Yanchao, Chang, Yongsheng, Yu, Kai-jiang, Findley, Brianna G., Berglund, Eric D., Wang, Rui-tao, Guo, Hongbo, Chen, Hong, Li, Xu, Kaufman, Randal J., Yan, Jianqun, Liu, Tiemin, Williams, Kevin W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319716/
https://ncbi.nlm.nih.gov/pubmed/28028078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0533
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados