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Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia
Whether neuronal inositol-requiring enzyme 1 (Ire1) is required for the proper regulation of energy balance and glucose homeostasis is unclear. We found that pro-opiomelanocortin (Pomc)–specific deficiency of Ire1α accelerated diet-induced obesity concomitant with a decrease in energy expenditure. T...
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| Publicado no: | Diabetes |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319716/ https://ncbi.nlm.nih.gov/pubmed/28028078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0533 |
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