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Vitamin C enhances the expression of IL17 in a Jmjd2–dependent manner

Previously, we reported that vitamin C facilitates the CpG demethylation of Foxp3 enhancer in CD4(+)Foxp3(+) regulatory T cells (Tregs) by enhancing the activity of a DNA demethylase ten-eleven-translocation (Tet). However, it is not clear whether vitamin C affects other helper T cell lineages like...

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Dades bibliogràfiques
Publicat a:BMB Rep
Autors principals: Song, Mi Hye, Nair, Varun Sasidharan, Oh, Kwon Ik
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Biochemistry and Molecular Biology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319665/
https://ncbi.nlm.nih.gov/pubmed/27931518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.1.193
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