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Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

Formation of amyloid fibrils underlies a wide range of human disorders, including Alzheimer's and prion diseases. The amyloid fibrils can be readily detected thanks to thioflavin T (ThT), a small molecule that gives strong fluorescence upon binding to amyloids. Using the amyloid fibrils of Aβ40...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:R Soc Open Sci
Päätekijät: Xue, Christine, Lin, Tiffany Yuwen, Chang, Dennis, Guo, Zhefeng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Royal Society Publishing 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319338/
https://ncbi.nlm.nih.gov/pubmed/28280572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.160696
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