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Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation
Formation of amyloid fibrils underlies a wide range of human disorders, including Alzheimer's and prion diseases. The amyloid fibrils can be readily detected thanks to thioflavin T (ThT), a small molecule that gives strong fluorescence upon binding to amyloids. Using the amyloid fibrils of Aβ40...
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| Veröffentlicht in: | R Soc Open Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society Publishing
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319338/ https://ncbi.nlm.nih.gov/pubmed/28280572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.160696 |
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