Clarithromycin attenuates IL-13–induced periostin production in human lung fibroblasts

BACKGROUND: Periostin is a biomarker indicating the presence of type 2 inflammation and submucosal fibrosis; serum periostin levels have been associated with asthma severity. Macrolides have immunomodulatory effects and are considered a potential therapy for patients with severe asthma. Therefore, w...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Komiya, Kosaku, Ohta, Shoichiro, Arima, Kazuhiko, Ogawa, Masahiro, Suzuki, Shoichi, Mitamura, Yasutaka, Nunomura, Satoshi, Nanri, Yasuhiro, Yoshihara, Tomohito, Kawaguchi, Atsushi, Kadota, Jun-ichi, Rubin, Bruce K., Izuhara, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319114/
https://ncbi.nlm.nih.gov/pubmed/28219384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0519-8
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