Induction of Airway Allergic Inflammation by Hypothiocyanite via Epithelial Cells

Hypothiocyanite (OSCN(−)) serves as a potent innate defense system against microbes in the lungs. OSCN(−) is generated by the catalysis of peroxidases using thiocyanate transported via several anion transporters, including pendrin/SLC26A4 and hydrogen peroxide (H(2)O(2)) generated by Duox1 and Duox2...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Suzuki, Shoichi, Ogawa, Masahiro, Ohta, Shoichiro, Nunomura, Satoshi, Nanri, Yasuhiro, Shiraishi, Hiroshi, Mitamura, Yasutaka, Yoshihara, Tomohito, Lee, James J., Izuhara, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207149/
https://ncbi.nlm.nih.gov/pubmed/27864363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.746909
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