Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression

BACKGROUND: Operational tolerance is an alternative to lifelong immunosuppression after transplantation. One strategy to achieve tolerance is by T regulatory cells. Safety and feasibility of a T regulatory type 1 (Tr1)-cell—based therapy to prevent graft versus host disease in patients with hematolo...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Mfarrej, Bechara, Tresoldi, Eleonora, Stabilini, Angela, Paganelli, Alessia, Caldara, Rossana, Secchi, Antonio, Battaglia, Manuela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Methodology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319067/
https://ncbi.nlm.nih.gov/pubmed/28222739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1133-8
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