C-terminal truncation of the retinoblastoma gene product leads to functional inactivation.

Mutational inactivation of the retinoblastoma (RB) gene has been implicated in the genesis of retinoblastoma, osteosarcoma, and other human tumors. Our strategy has been to characterize naturally occurring mutants from tumor cells to pinpoint potential domains of RB protein crucial for tumor suppres...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Shew, J Y, Lin, B T, Chen, P L, Tseng, B Y, Yang-Feng, T L, Lee, W H
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1990
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53188/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688660/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.6
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