ロード中...
FOXM1 allows human keratinocytes to bypass the oncogene-induced differentiation checkpoint in response to gain of MYC or loss of p53
Tumour suppressor p53 or proto-oncogene MYC is frequently altered in squamous carcinomas, but this is insufficient to drive carcinogenesis. We have shown that overactivation of MYC or loss of p53 via DNA damage triggers an anti-oncogenic differentiation-mitosis checkpoint in human epidermal keratino...
保存先:
| 出版年: | Oncogene |
|---|---|
| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5318665/ https://ncbi.nlm.nih.gov/pubmed/27452522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.262 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|