Receptor class desensitization of leukocyte chemoattractant receptors.

To better define their regulation, formylpeptide and C5a chemoattractant receptor cDNAs were transiently expressed with high efficiency (approximately 35-54%) in human kidney cells. As in neutrophils, both receptors were active in elevating intracellular calcium (ED50 approximately 0.5-1 nM). Agonis...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Didsbury, J R, Uhing, R J, Tomhave, E, Gerard, C, Gerard, N, Snyderman, R
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53176/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1763071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11564
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