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Receptor class desensitization of leukocyte chemoattractant receptors.

To better define their regulation, formylpeptide and C5a chemoattractant receptor cDNAs were transiently expressed with high efficiency (approximately 35-54%) in human kidney cells. As in neutrophils, both receptors were active in elevating intracellular calcium (ED50 approximately 0.5-1 nM). Agonis...

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Bibliografische gegevens
Hoofdauteurs: Didsbury, J R, Uhing, R J, Tomhave, E, Gerard, C, Gerard, N, Snyderman, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1991
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53176/
https://ncbi.nlm.nih.gov/pubmed/1763071
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