Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation

BACKGROUND: Curcumin induces apoptosis and autophagy in different cancer cells. Moreover, chemical and biological experiments have evidenced that curcumin is a biologically active iron chelator and induces cytotoxicity through iron chelation. We thus hypothesized that curcumin may induce apoptosis a...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Yang, Chunguang, Ma, Xueyou, Wang, Zhihua, Zeng, Xing, Hu, Zhiquan, Ye, Zhangqun, Shen, Guanxin
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317247/
https://ncbi.nlm.nih.gov/pubmed/28243065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S126964
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