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Wip1 abrogation decreases intestinal tumor frequency in APC(Min/+) mice irrespective of radiation quality

Low linear energy transfer (low-LET) γ-ray exposure is a risk factor for colorectal cancer (CRC). Due to high-LET nature, energetic iron ions are expected to pose greater CRC risks to astronauts undertaking long duration space missions beyond low earth orbit (LEO). Wild-type p53-induced phosphatase...

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Publicat a:Radiat Res
Autors principals: Suman, Shubhankar, Moon, Bo-Hyun, Thakor, Hemang, Fornace, Albert J, Datta, Kamal
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317043/
https://ncbi.nlm.nih.gov/pubmed/25117622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13770.1
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