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Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine

Proliferative gastrointestinal (GI) tissue is radiation-sensitive, and heavy-ion space radiation with its high-linear energy transfer (high-LET) and higher damaging potential than low-LET γ-rays is predicted to compromise astronauts’ GI function. However, much uncertainty remains in our understandin...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Kumar, Santosh, Suman, Shubhankar, Fornace, Albert J., Datta, Kamal
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196540/
https://ncbi.nlm.nih.gov/pubmed/30275302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807522115
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