NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells

Autophagy is a cellular survival mechanism that involves the catabolic degradation of damaged proteins and organelles during periods of metabolic stress, and when overly stimulated, commonly contributes to cell death. Nitric oxide (NO), a potent cellular messenger, participates in a complex mechanis...

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Détails bibliographiques
Publié dans:Cell Death Discov
Auteurs principaux: Zhu, Lingqun, Li, Linlin, Zhang, Qianbing, Yang, Xiao, Zou, Zhiwei, Hao, Bingtao, Marincola, Francesco M, Liu, Zhengjun, Zhong, Zhuo, Wang, Meng, Li, Xiaoxuan, Wang, Qianli, Li, Keyi, Gao, Wenwen, Yao, Kaitai, Liu, Qiuzhen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317009/
https://ncbi.nlm.nih.gov/pubmed/28243469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.11
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