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Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans

Stress-response pathways have evolved to maintain cellular homeostasis and to ensure the survival of organisms under changing environmental conditions. Whereas severe stress is detrimental, mild stress can be beneficial for health and survival, known as hormesis. Although the universally conserved h...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kumsta, Caroline, Chang, Jessica T., Schmalz, Jessica, Hansen, Malene
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316864/
https://ncbi.nlm.nih.gov/pubmed/28198373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14337
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