A rapid method for determination of endoproteinase substrate specificity: specificity of the 3C proteinase from hepatitis A virus.

The preferred amino acid residues at the P'1 and P'2 positions of peptide substrates of the 3C proteinase from hepatitis A virus (HAV-3C) have been determined by a rapid screening method. The enzyme was presented with two separate mixtures of N-terminal acetylated peptides, which were identical in s...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Petithory, J R, Masiarz, F R, Kirsch, J F, Santi, D V, Malcolm, B A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11510
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