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Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination

Diverse cellular stressors have been observed to trigger site-specific ubiquitination on several ribosomal proteins. However, the ubiquitin ligases, biochemical consequences, and physiologic pathways linked to these modifications are not known. Here, we show in mammalian cells that the ubiquitin lig...

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Publicat a:Mol Cell
Autors principals: Juszkiewicz, Szymon, Hegde, Ramanujan S.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316413/
https://ncbi.nlm.nih.gov/pubmed/28065601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.039
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