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Nimodipine-Loaded Pluronic(®) Block Copolymer Micelles: Preparation, Characterization, In-vitro and In-vivo Studies
Nimodipine (NM), as a lipophilic calcium channel blocker indicated for the prevention and treatment of neurological disorders, suffers from an extensive first pass metabolism, resulting in low oral bioavailability. Polymeric micelles, self-assembled from amphiphilic polymers, have a core-shell struc...
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| Publicado no: | Iran J Pharm Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Shaheed Beheshti University of Medical Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5316244/ https://ncbi.nlm.nih.gov/pubmed/28243263 |
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