Nimodipine-Loaded Pluronic(®) Block Copolymer Micelles: Preparation, Characterization, In-vitro and In-vivo Studies

Nimodipine (NM), as a lipophilic calcium channel blocker indicated for the prevention and treatment of neurological disorders, suffers from an extensive first pass metabolism, resulting in low oral bioavailability. Polymeric micelles, self-assembled from amphiphilic polymers, have a core-shell struc...

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Detalles Bibliográficos
Publicado en:Iran J Pharm Res
Autores principales: Sotoudegan, Farzaneh, Amini, Mohsen, Faizi, Mehrdad, Aboofazeli, Reza
Formato: Artigo
Lenguaje:Inglês
Publicado: Shaheed Beheshti University of Medical Sciences 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316244/
https://ncbi.nlm.nih.gov/pubmed/28243263
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