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Improving acetyl-CoA biosynthesis in Saccharomyces cerevisiae via the overexpression of pantothenate kinase and PDH bypass

BACKGROUND: Acetyl-CoA is an important precursor in Saccharomyces cerevisiae. Various approaches have been adopted to improve its cytosolic level previously with the emphasis on engineering the “acetyl-” part of acetyl-CoA. To the best of our knowledge, there have been no reports on engineering the...

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Detalhes bibliográficos
Publicado no:Biotechnol Biofuels
Main Authors: Liu, Wenshan, Zhang, Bo, Jiang, Rongrong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316175/
https://ncbi.nlm.nih.gov/pubmed/28239413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-017-0726-z
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