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ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae

BACKGROUND: With increasing concern about the environmental impact of a petroleum based economy, focus has shifted towards greener production strategies including metabolic engineering of microbes for the conversion of plant-based feedstocks to second generation biofuels and industrial chemicals. Sa...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Rodriguez, Sarah, Denby, Charles M., Van Vu, T., Baidoo, Edward E. K., Wang, George, Keasling, Jay D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778282/
https://ncbi.nlm.nih.gov/pubmed/26939608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0447-1
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