Elderly-onset hereditary pulmonary alveolar proteinosis and its cytokine profile

BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by surfactant accumulation, and is caused by disruption of granulocyte/macrophage colony-stimulating factor (GM-CSF) signaling. Abnormalities in CSF2 receptor alpha (CSF2RA) were reported to cause pediatric heredit...

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Publicado en:BMC Pulm Med
Autores principales: Ito, Masayuki, Nakagome, Kazuyuki, Ohta, Hiromitsu, Akasaka, Keiichi, Uchida, Yoshitaka, Hashimoto, Atsushi, Shiono, Ayako, Takada, Toshinori, Nagata, Makoto, Tohyama, Jun, Hagiwara, Koichi, Kanazawa, Minoru, Nakata, Koh, Tazawa, Ryushi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316164/
https://ncbi.nlm.nih.gov/pubmed/28212655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-017-0382-x
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